Antifungal Nizoral (ketoconazole)
Nizoral is generically known as ketoconazole. It is an antifungal drug which fights against the fungal infections.
Composition of Nizoral
Nizoral is a broad-spectrum synthetic antifungal drug available in white scored tablets, each composed of 200 mg ketoconazole. Inactive ingredients present in nizoral are magnesium stearate, colloidal silicon dizoxide, microcrystalline cellulose, povidone, starch and lactose.
Uses of Nizoral
Nizoral is used to treat some serious infections caused by fungus. Ketoconazole is present in the class of medicines known as azole antifungals. It works by preventing the growth of the fungus. Nizoral should not be used for the treatment of fungal infections of toenails or fingernails, skin or brain. It may also be used for the treatment of advanced prostate cancer.
How to use Nizoral
The medication guide given by the doctor should be carefully read before starting the use of ketoconazole. Consult your doctor or physician in case of any queries. This medicine has to be taken orally as instructed by your doctor, generally once in a day. This medicine can be taken with or without meal, but consuming it with meal reduces the chances of stomach upset. The dosage and course of the treatment depends on your response to drug, medical condition and other drugs you may be consuming. This works provides the maximum benefit when the amount of the drug remains constant in the body. Therefore this drug has to be taken at regular intervals.
Nausea and vomiting may usually occur. When this drug is taken at high doses; it may cause an unlikely problem to the adrenal gland (adrenal deficiency), a decrease in sperm synthesis or a fall in the testosterone levels. Ketoconazole may increase the danger to the existing problems related to the functioning of the adrenal glands. Some unusual or rare side-effects of nizoral include: weakness, abnormal tiredness, dizziness on standing, weight loss, diarrhea, menstrual cycle changes, decreased libido or tender/enlarged breasts in males. Ketoconazole has caused fatal liver problems in rare cases. Consult your doctor right away if you develop liver problems such as dark urine, abdominal pain, yellowing eyes/skin, light colored stools, persistent vomiting/nausea or loss of appetite.
Contra-indications of Nizoral
Ketoconazole can cause serious drug interactions. Therefore the use of nizoral is only recommended when no other treatments are going on. Ketoconazole should not be used with some other drugs such as ranolazine, methadone, quinidine, pimozide, cisapride etc. Before the intake of this drug, inform your doctor about your medical history, particularly of: alcohol use, liver disorders, low level of testosterone, low cortisol levels, low production of stomach acid. Patients who show allergic reactions to ketoconazole or other antifungal medicines like itraconazole or fluconazole.
Nizoral and Pregnancy
It is unknown whether ketoconazole can harm a fetus. Inform your doctor if you are expecting or planning to conceive in near future while using this drug. Ketoconazole can be excreted into the breast milk and can cause possible harm to the breastfed baby. Therefore breastfeeding is not advisable during the intake of this medication.
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