Antibiotic Zyvox (linezolid)
The generic name of Zyvox is linezolid. It is a synthetic antibiotic which is very effective against several bacteria. It works by preventing bacterial growth. It is effective against Enterococcus faecium, Staphylococcus aureus, Streptococcus pneumonia, Streptococcus agalactiae, Streptococcus pyogenes, etc.
Uses of Zyvox
Zyvox is used in several conditions and diseases like:
- Complicated as well as uncomplicated skin as well as skin structure infections
- Vancomycin- resistant Enterococcus faecium infections
Side effects of Zyvox
There are some mild and common side effects attached to Zyvox. They are:
Other less common, but possible side- effects of Zyvox are:
- Abdominal pain
- Loose stool
There are also some serious side- effects attached to Zyvox. They are:
- Decreases white blood corpuscles
- Impairment in vision
- Lactic acidosis
- Serotonin syndrome
- Peripheral neuropathy
- Severe allergic reactions
- Clostridium difficile related colitis or diarrhea
There are certain conditions in which one must not take Zyvox. They are:
- Hypoglycemia is reported patients who have diabetes and take insulin or oral hypoglycemic agents. So, it’s better to avoid this drug if you have diabetes.
- The patients who take medications to increase blood pressure must not take this drug.
- It should not be used to treat catheter-related bloodstream infections as well as catheter site infections.
- It should not be given to the patients who have bone marrow suppression or it develops during the course of treatment, the treatment should be discontinued.
Pregnancy and Zyvox
There is not much known about the effects of Zyvox on the unborn child. But, it would be better to discuss all the possible effects and side- effects of Zyvox on the unborn baby before taking it. It is also not known whether it passes into the breast milk or not. So, you must discuss it with your doctor if you are a breast feeding mother.
Drug Interactions with Zyvox
There are several drugs that interact with Zyvox and cause unwanted effects. They are:
- Antidepressants like paroxetine (Paxil), amitryptline, nortryptline, fluxetine (Prozac), bupropion (Zyban, Wellbutrin), pain management drugs like methadone, tramadol and mirtazapine (Remeron).
- Pseudoephedrine, ephedrine, phenylephrine and phenylpropanolamine.
- For pneumonia and skin infections: 600 mg orally or intravenous infusion in every 12 hours for about 10 to 14 days.
- For uncomplicated skin infections: 400 to 600 mg orally in every 12 hours for about 10 to 14 days.
- For Vancomycin- resistant Enterococcus faecium infections: 600 mg oral ingestion or intravenous infusion in every 12 hours for about 14 to 28 days.