Antibiotic Chloromycetin (chloramphenicol)
The generic name of Chloromycetin is Chloramphenicol. This medication is a man-made antibiotic. It helps in slowing down the growth of bacteria by not letting them produce proteins that they require for their existence and survival. This drug is useful against H. Influenzae, S. typhi, Neisseria species, E. coli, Streptococcus species, Staphylococcus, and rickettsia. This medication was approved by the FDA in December, 1950.
Composition of Chloromycetin
Chloromycetin is found in the following forms:
- Eye drops or eye ointments
- Vial powder for the intravenous injection form
The active ingredient in this medication is Chloramphenicol. Each vial comprises a sterile solution up to 100 mg of chloramphenicol/mL. A single gram of chloramphenicol sodium succinate has about 52 mg sodium in it.
Uses of Chloromycetin
This medication is manly used for the treatment of eye infections caused by bacteria. It is a type of antibiotic which prevents the growth of bacteria.
This antibiotic drug can only be used in case of bacterial infections. They will not work for the treatment of other types of eye infections. The misuse and the unnecessary usage of this drug can reduce its effectiveness.
Side-effects of Chloromycetin
There may be many unwanted effects resulting from the use of Chloromycetin which may require medical attention. Some of them may not require any medical attention. As the medication starts getting used to the body, the side-effects may eventually disappear.
Some of the rare side-effects found in babies are mentioned below:
- Bloated stomach
- Low temperature of the body
- Gray skin colour
- Uneven breathing
Some of the less common side-effects are:
- Fever along with sore throat
- Pale skin
- Unusual bruising or bleeding
- Unusual weakness or tiredness
- Vomiting or nausea
The above mentioned side-effects may even be seen after weeks and months of stopping the use of chloramphenicol.
Some rare side-effects are as follows:
- Fever, difficulty while breathing, or skin rash
- Blurred vision, loss of vision, or eye pain
- Delirium, headache, or confusion
- Tingling, numbness, weakness, or burning pain in the feet or hands
The health care professional will provide ways in which these side-effects can be reduced. The patient should immediately check with the health care professional in case the side-effects are bothersome.
Contraindications of Chloromycetin
There are restricted conditions where the use of Chloromycetin is prohibited. The conditions where the patient must be refrained from using this medication are:
- Allergic reaction to chloramphenicol amphenicols
- G6PD Deficiencies
- Anaemia caused by Pyruvate Kinase
Chloromycetin and pregnancy
The FDA has listed this medication in the pregnancy category C. There have been no evidences of any controlled data among human pregnancies. Though there has been no report of birth defects, there have been adverse effects resulting from the use of Chloromycetin in late pregnancy.